Detection of multilocus selection in genes involved in alimentary processes in Humans.

 We propose a postdoctoral position financed by the French Agence Nationale de la Recherche, project “NUTGENEVOL”. This project is a joint collaboration between the laboratories “Ecologie, Systématique et Evolution” located at the “Université de Paris-Sud” in Orsay near Paris (team of Frédéric Austerlitz) and “Eco-Anthropology” located at the National Museum of Natural History in Paris (team of Evelyne Heyer).

This position is opened for two years, with a beginning before May 1st 2010 (the postdoc can potentially start later but will not in that case be funded for two full years). The NUTGENEVOL project consists in studying the selection pressures that occurred on genes involved in alimentary processes. The first aim of the postdoctoral position would be to focus on the multilocus analysis of selective pressure occurring on these genes. The other aspect of the project would be to analyse whether the genes under selection have specific functions in the gene networks involved in these processes.

 These selective pressures are connected with the changes in alimentary diets in humans. Indeed, before the major Neolithic transition (~10,000 yBP), our hunter-gatherer ancestors had a meat-based diet, poor in carbohydrates and rich in protein. Therefore, genes favouring insulin resistance and gluconeogenesis were selected for, in order to constantly maintain sufficient level of glucose in the blood. These potentially “thrifty” genes may now be detrimental in urbanized societies, because under the present high carbohydrate diet, insulin resistance and gluconeogenesis may lead to metabolic disorders such as type II diabetes, obesity, and hypertension. To detect the selective pressures that occurred on these genes, we have obtained sequence polymorphism data for 11 candidate genes involved in these traits in two Central Asian populations: one pastoralist and one agriculturist population, for which differences in diet may have lead to different selective pressures on such genes. We are currently also obtaining data on polymorphism of DNA SNPs: 660,000 SNPs (Illumina, Human 660W Quad v1.0) in these two populations.

 All the traits involved in this study are polygenic traits involved in gene networks, and a multilocus approach to detect selection would thus seem especially appropriate. Therefore, the postdoctoral position within this project would first consist in searching for selection that acts jointly on combination of SNPs in the same or different genes, using the data on candidate genes and SNPs. This will be performed for instance through the study of linkage disequilibrium between these loci. Other methodological developments may be considered. Similar studies could also be performed in public databases such as HAPMAP. For validation, the methods may be also applied to simulated data, using a program developed by other people from the group.

 Another aspect of the postdoctoral position will consist for the genes under selection in analysing their position in the network, in order to test whether the position in the network could influence the level of selection occurring on these genes. A particular emphasis will be put on studying the level of pleiotropy of these genes, as selective pressures may differ for genes involved in one vs. several different functions.

This research on gene networks will be mostly performed through searches in public databases.

 Salary should be around 1900 euros per month. Interested candidates should send their application preferentially by email to Frédéric Austerlitz (see coordinates below). Please include a CV, a brief letter explaining your motivations and the coordinates of two or three potential references. Applications should be sent before November 15th.

Please also do not hesitate to ask for further details at this address.

 Frédéric Austerlitz

Laboratoire Ecologie, Systématique et Evolution UMR CNRS/Université Paris Sud/AgroParisTech 8079 Université Paris-Sud, Bâtiment 360

F-91405 Orsay cedex, France

Tel : +33 1 69 15 77 20 / Fax : +33 1 69 15 46 97 frederic.austerlitz@u-psud.fr

webpages :

Fréderic Austerlitz: http://www.ese.u-psud.fr/pages_perso/spip.php?article26

Evelyne heyer:

http://www.ecoanthropologie.cnrs.fr/spip.php?article300&langÊ

RESEARCH POSITIONS IN GENOMICS, BIOINFORMATICS, AND EVOLUTION

Several openings are available to work on the project entitled "Evolutionary and functional analysis of polymorphic inversions in the human genome", selected for 5-year funding through an ERC Starting Grant from the European Research Council. This project aims to improve our understanding on the impact of inversions in the human genome at multiple levels by combining methods of different disciplines, such as next-generation genomic techniques, bioinformatics, population genetics, and molecular evolution. Successful candidates will form part of a young, highly dynamic, and interdisciplinary research team located at the Institute of Biotechnology and Biomedicine of the Universitat Autònoma de Barcelona (http://ibb.uab.es/).

Available positions: We are seeking very motivated individuals with a doctorate or university degree and research experience in the following relevant fields:

1. Postdoc expert in high-throughput genomics and molecular biology techniques.

2. Postdoc with strong background in bioinformatic analysis of DNA sequences.

3. Postdoc with good knowledge in population genetics and molecular evolution.

4. PhD student in functional genomics and gene-expression analysis.

5. Research technician/Lab manager with basic training in molecular biology.

Conditions: Salaries will be competitive according to profile and experience of candidates. Duration of contracts will depend on the specific position, ranging from 1 to 5 years.

Starting date:All positions are available from January 2010.

Application: Send a CV and a one-paragraph summary of previous research experience to Mario Cáceres (mcaceres@icrea.cat).

Application deadline: Please send application as soon as possible, preferably before October 31 2009.

SFI has openings for several "core-funded" postdoctoral positions this year. These are in the SFI Omidyar Fellows Program. In addition, David Krakauer and I have an opening for a postdoc on an NSF conflict dynamics grant, also at the Santa Fe Institute. This is a theory position. Position announcements are below.

http://www.santafe.edu/~jflack

POSTDOCTORAL POSITION ANNOUNCEMENTS

POSTDOC IN DYNAMICS OF CONFLICT IN BIOLOGICAL AND SOCIAL SYSTEMS The Santa Fe Institute has an opening for a postdoctoral fellowship in the dynamics of conflict. The position is funded through the National Science Foundation and is for two to three years.

The postdoctoral researcher will work closely with faculty Jessica Flack and David Krakauer analyzing large data sets and developing mathematical models. We expect the candidate to have a strong background and publication record in either dynamical systems, and or statistical physics, applied to biological or social systems. The work will be grounded in high resolution conflict time series, and involve the application of ideas from Bayesian statistics, information theory, game theory, dynamical systems, and the theory of collective phenomena. The postdoc will be required to spend approximately 80% of his/ her time on conflict related projects. For the remaining 20% of time, the postdoc is encouraged to collaborate with members of the larger SFI community.

The postdoc will be joining a research project that seeks to explain how complex social systems evolve, and how these systems minimize the dissipative effects of conflict through mechanisms of conflict management. In previous publications this group has made extensive use of non-parametric statistics, network methods, and information theory to study robustness in complex systems. Strong analytical skills and the ability to work with both large data sets and parsimonious models will be favored. The salary for the position will be 55K with standard SFI benefits, and funds are available to assist with travel and to bring collaborators to SFI.

To apply for this position, please send an email containing your CV and a two-page research statement to Drs. Jessica Flack and David Krakauer at jflack@santafe.edu. Please include names of three references and ask recommenders to send their letters to the above email address. The deadline for receipt of applications is December 15.

The Santa Fe Institute is an equal opportunity employer. For more information about the institute see http://www.santafe.edu.

MPI-EVA Primate population genetics

Applications are invited for a two-year postdoctoral position investigating the population histories of wild primate populations in the molecular genetics lab in the Primatology department of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.

The project will involve high-throughput sequencing and analysis of large DNA sequence datasets, and relevant experience would be advantageous.

Starting date is January 2010 or soon thereafter. Support is provided in the form of a tax-free stipend; the exact amount depends upon age and years of post-Ph.D experience. Leipzig is a charming city with a lively cultural scene and a low cost of living and the MPI-EVA is an outstanding place to do research. For more information on research in this group, see http://www.eva.mpg.de/primat/files/genetics.htm

Enquiries and applications in the form of a cv, brief statement of research interests, relevant publications and contact information for three references should be sent via email to Linda Vigilant at vigilant@eva.mpg.de

Linda Vigilant

Max Planck Institute for Evolutionary Anthropology Deutscher Platz 6

04103 Leipzig Germany

http://email.eva.mpg.de/%7Evigilant/

A postdoctoral position is available immediately in the research group of Joshua Akey in the Department of Genome Sciences at the University of Washington. The position is supported by NIH stimulus funds to create the Northwest Genomics Center and is available for two years, with the possibility of extension beyond this time frame.

The Northwest Genomics Center, under the direction of Debbie Nickerson, Phil Green, Jay Shendure and Mark Rieder, will resequence the exomes of 5,000 genomic DNA samples derived from well-phenotyped NHLBI cohorts (http://www.nhlbi.nih.gov/recovery/media/stimulus.htm).

This exciting data set will provide rich opportunities for the postdoctoral candidate to pursue questions related to human evolutionary history, natural selection, and genotype-phenotype relationships. The ideal candidate will have a strong background in population genetics or in relevant areas of mathematics and statistics, strong computational and programming skills, experience in analyzing large data sets, and be self-motivated and independent.

The Department of Genome Sciences offers an outstanding intellectual environmental for trainees. Research in the department addresses questions in biology and medicine by developing and applying genetic, genomic, and computational approaches that take advantage of genomic information. Departmental faculty are exceptionally distinguished and include eight members of the National Academy of Sciences and one Nobel laureate. In November 2006 the entire Department of Genome Sciences moved to the newly constructed, state of the art Foege Building (http://www.gs.washington.edu/ and http:// www.gs.washington.edu/faculty/index.htm). (posted 10/13/09)

POSTDOCTORAL FELLOWSHIPS IN EVOLUTIONARY BIOLOGY AND RELATED FIELDS We are now accepting proposals for Postdoctoral Fellowships at The National Evolutionary Synthesis Center (NESCent). We are looking to fund innovative approaches to outstanding problems in evolutionary biology. Proposals are due December 1. For more information, please see our website at https://www.nescent.org/science/proposals.php.

The Department of Geology and Geophysics at Yale University (http://www.geology.yale.edu) seeks applicants for a postdoctoral fellowship in research that links geosciences (studies of the solid earth, oceans, atmosphere, climate, and the evolution of life) with other sciences, including, but not limited to, astronomy and astrophysics; environmental studies; physics; chemistry; biology; engineering; anthropology; medical science and public health; economics and political science.

The Harris County Medical Examiner’s Office (HCMEO) is pleased to announce a one-year post-doctoral fellowship in Forensic Anthropology. The HCMEO Anthropology Division consists of one board certified forensic anthropologist, two doctoral level anthropologists and an identification specialist. The division provides services in skeletal biology and trauma analysis, unidentified decedent processing, death scene response, mass disaster preparedness and epidemiology.

The Department of Biostatistics and Epidemiology at the University of Oklahoma Health Science Center invites applications for a postdoctoral fellowship, available immediately, in statistical genetics/genetic epidemiology. The position will focus on mapping genes for cardiovascular diseases and their risk factors in the investigation of major genetic effects as well as gene-gene and gene-environment interactions in both genome-wide association and pathway-based genetic analyses.

Postdoctoral Position To Study Sexual Selection and Social Evolution

A NSF-funded postdoctoral position is currently available in the lab of Suzanne Alonzo (PI) at the Department of Ecology and Evolutionary Biology at Yale University to develop theory on how individual social or behavioral interactions affect evolutionary dynamics. The postdoctoral researcher will work independently and in collaboration with the PI to determine the precise questions to be addressed. A Ph.D.

in evolution, ecology, or mathematical biology is required. A background in sexual selection, social evolution or evolutionary ecology is preferred. Applicants should have a background in evolutionary or ecological theory and have previous experience developing mathematical models. Individuals with experience using adaptive dynamics, game theory or quantitative genetics are especially encouraged to apply.

Application deadline is November 1, 2009. Position will remain open until filled. In the cover letter, applicants are asked to describe their theoretical background and experience with mathematical modeling explicitly. Please submit a curriculum vitae, brief statement of research interests, up to 3 relevant manuscripts and contact information for 3 references to Suzanne H. Alonzo by email(Suzanne.Alonzo@Yale.edu). Please put: "Sexual Selection and Social Evolution Postdoc" in the subject line.

Yale University is an Equal Opportunity/Affirmative Action Employer. Men and women of diverse racial/ethnic backgrounds and cultures are encouraged to apply.

"Suzanne H. Alonzo" <Suzanne.Alonzo@Yale.edu>

POSTDOC IN POPULATION GENETICS, UNIVERSITY OF CHICAGO

A postdoctoral position in population genetics is available in Molly Przeworski's group at the University of Chicago. The specific project is flexible. Current work in the group focuses on a wide range of topics, from the study of natural selection in humans and other primates to understanding patterns and processes of recombination. For more information, see http://przeworski.uchicago.edu/.

Our group shares space and weekly lab meetings with those of Jonathan Pritchard and Matthew Stephens and enjoys close ties with other members of the Human Genetics and Ecology & Evolution departments, notably Anna Di Rienzo, Dick Hudson and Carole Ober. Moreover, it benefits from the large and outstanding community of researchers in population genetics, statistics and genomics at the University of Chicago.

Applicants for the position must have either a background in theoretical population genetics, with experience in data analysis,

or come from a quantitative field (such as statistics or computer science) and have a strong interest in genetics and evolution. Programming and bioinformatics skills are essential. Informal inquiries as well as applications (including a CV, copies of relevant publications and two letters of recommendation) should be emailed to Molly Przeworski at <mfp@uchicago.edu>. The starting date is Spring-Summer 2010.

Stanford University: Human Population Genetics, Domestication Genomics, and Statistical Genomics (multiple positions)

Several post-doctoral positions are available in the laboratory of Carlos D. Bustamante. The lab focuses on developing and deploying novel statistical and computational methods for analyzing genome-wide patterns of variation within and among species to address fundamental questions in evolutionary and human genomics. We are moving to the Genetics Department at the Stanford University School of Medicine in January 2010, and several positions are available including:

1) Statistical population genetics. The successful applicant(s) for this position will work on developing novel approaches for population genetic inference from whole genome sequence data including methods for demographic inference and for detecting signatures of selection in the human genome. Strong programming skills in C/C++, excellent knowledge of probability theory and stochastic processes, and good familiarity with theoretical/computational statistics is required. The ideal candidate would have a Ph.D. with emphasis on theoretical population genetics, human genomics, statistical genetics/genomics, or computational statistics. S/he will work on both publicly available data (e.g., 1000 Genomes) as well as on genomes to be sequenced through other collaborative efforts. There is also ample opportunity for collaboration with the labs of Andy Clark (Cornell), Rasmus Nielsen (Berkeley), Alon Keinan (Cornell), and John Novembre (UCLA) as part of these NIH funded positions.

2) Human population genetics of the Americas. A major thrust of the lab in the coming years will be characterizing patterns of human genetic variation in North, Central, and South America as well as the Caribbean in indigenous American and admixed Hispanic/Latino and African-American populations. Post-doctoral positions are available for scientists interested in both dry and wet lab research. The ideal candidate will have a Ph.D. in human genetics/genomics, anthropological genetics, and/or medical genetics. The applicants will have opportunities for collaborative field and lab research including projects with Andres Ruiz-Linares (UCL), Esteban Burchard (UCSF), Sarah Tishkoff (U. Penn), and Harry Ostrer (NYU)

3) Domestication Genomics of rice. Post-doctoral positions are available to work on domestication genomics of Oryza sativa (Domesticated Asian rice) and its wild relatives. These include joining a collaborative NSF funded project with Micheal Purugganan (NYU) and Barbara Schall (Wash U.) to fine map signatures of selection around domestication QTLs. There is also an opportunity to join a project with Susan McCouch (Cornell), Georgia Eizenga (USDA), and Anna McClung (USDA) to identify genes underlying 26 agronomically important traits in rice using high density genotyping arrays being developed by the project. The successful applicants will have a Ph.D. in quantitative genetics / genomics, strong programming and statistical genomics skills, and possess inter personal skills necessary to work as part of large collaborative networks.

4) Population and quantitative genomics of dog domestication. A post- doctoral position is available to work with me, Adam Boyko (Cornell/ Stanford), Bob Wayne (UCLA), John Novembre (UCLA), and Elaine Ostrander (NHGRI) on population genetics and domestication genomics of dogs. For several years, our collaborative groups has worked to sample, genotype, (and soon sequence) thousands of breed-affiliated dogs, village dogs, and wolves from throughout the world. The successful applicant will work closely with our collaborative group to analyze these data and identify geographic signatures of dog domestication and genomic regions potentially containing QTLs for breed defining and domestication traits.

To apply for these positions please send an email with a single collated PDF to Carlos D. Bustamante (cdb28 [at] cornell.edu) including (1) a C.V., (2) statement of research interest (stating which position(s) you are interested in), (3) names and emails for three references, and (4) reprints for 1-2 papers. Note: Any application not submitted as a PDF will be discarded.

The ideal start date for these positions is early Spring 2010, but there is some flexibility .

Carlos D. Bustamante, Professor

Biological Statistics and Computational Biology Cornell University http://bustamantelab.cb.bscb.cornell.edu/

After 1/1/10:

Department of Genetics

Stanford University School of Medicine

Anthropological Genetics Postdoctoral Position

Northwestern University

 The Center for Genetic Medicine and Department of Anthropology at Northwestern University seeks applicants for a postdoctoral research position in anthropological / population genetics.  The successful candidates will contribute to the data collection and analysis of a highly collaborative and multi-institution NSF funded International Polar Year project to examine the geographic patterns of variation in humans along the North Slope of Alaska.  The preferred candidate will have relevant background in anthropology, genetics, or related field, but all interested applicants are encouraged to apply.   Applicants must possess good communication skills and be fluent in both spoken and written English.  Applicants will be expected to be self-motivated, work both independently and collaboratively, publish research results in peer-reviewed scientific journals, and contribute to grant proposals. Applicants should send a statement of their research interests and experience, their curriculum vitae, and the names, email addresses and phone numbers of three references to Dr. M. Geoffrey Hayes at ghayes@northwestern.edu with “Anthropological Genetics Postdoc Position” in the subject field.  Review of applications will begin immediately and continue until the positions are filled.

Statistical Genetics / Genetic Epidemiology Postdoctoral Positions

Northwestern University

 The Center for Genetic Medicine and Feinberg School of Medicine at Northwestern University seeks applicants for multiple postdoctoral research positions.  The successful candidates will contribute to the development and implementation of analytic methods as part of several highly collaborative and multi-institution genome-wide association studies for common, complex human diseases, and related metabolic, cardiovascular, reproductive, and development/growth phenotypes.  The preferred candidates will have relevant background in genetics, statistics or related field, and experience with large data sets, but all interested applicants are encouraged to apply.   Programming experience a plus.  Applicants must possess good communication skills and be fluent in both spoken and written English.  Applicants will be expected to be self-motivated, work both independently and collaboratively, publish research results in peer-reviewed scientific journals, and contribute to grant proposals. Applicants should send a statement of their research interests and experience, their curriculum vitae, and the names, email addresses and phone numbers of three references to Dr. M. Geoffrey Hayes at ghayes@northwestern.edu with “StatGen/GenEpi Postdoc Position” in the subject field.  Review of applications will begin immediately and continue until the positions are filled.

Duke University

Department of Evolutionary Anthropology

Associate in Research

Applications are invited for a postdoctoral position to study the evolution of olfactory communication in primates. The post is funded by the National Science Foundation and is immediately available, for one year, with the possibility of extension. The work combines behavioral, chemical, and genetic approaches, and is conducted at Duke University (http://www.baa.duke.edu/) and its Lemur Center (http://lemur.duke.edu/ ). Previous and current projects have focused on the ring-tailed lemur and the mandrill, with planned extensions to other species.

The successful candidate will have earned a PhD in a relevant discipline at the time of appointment. Applicants should have a strong background in one or more of the following areas: animal behavior, behavioral ecology, chemical ecology, evolutionary biology, population genetics, proteomics.

Please email an application to Christine Drea (cdrea@duke.edu), consisting of a cover letter summarizing your qualifications and interests, a curriculum vitae, representative reprints or preprints, and the names and contact information for two references. Evaluation of applicants will begin immediately and will continue until the position is filled. Duke University is an Affirmative Action/Equal Opportunity Employer.

Christine Drea <cdrea@duke.edu>

The Leibniz Institute for Zoo and Wildlife Research (IZW) in Berlin is Germany's premier wildlife research institute and funded by the federal government of Germany and the state government of Berlin. The IZW focuses on the life histories and mechanisms of evolutionary adaptations of mammals and birds and their conservation in natural and anthropogenically influenced environments. The institute operates within the fields of evolutionary ecology and genetics, wildlife diseases and reproduction biology and management, has excellent facilities and is currently expanding its research programme (http://www.izw-berlin.de).

The institute has received funding for a major network project on "olfactory mate choice - immune system, olfactory receptors and their adaptive value" under the leadership of Prof Dr Simone Sommer. Olfaction plays a central role for mate choice in mammals, but there is a lack of understanding of the underlying proximate and ultimate aspects of olfactory signal evolution. Recent studies highlighted the importance of the major histocompatibility complex (MHC) for female choice which raises the question how volatiles, olfactory receptors and the MHC co-evolved in mammalian mating systems. The overall project will use a broad genomic and immunological approach to analyse this question, thereby combining state-of-the-art transcriptome analyses with detailed immunological studies and extensive field work in long-term projects on two species with contrasting social and mating systems, the greater sac-winged bat in Costa Rica and the spotted hyena in Tanzania. The network consists of the IZW (olfactory mate choice, Prof Dr Simone Sommer, PD Dr Christian Voigt, Dr Marion East, Prof Dr Heribert Hofer), the Leibniz Institute for Age Research in Jena (transcriptome analysis, PD Dr Matthias Platzer), the Charité in Berlin (immunogenetics, Prof Dr Andreas Ziegler, Dr. Barbara Uchanska-Ziegler) and the University of Geneva, Switzerland (olfactory receptor genes, Prof Dr Michel Milinkovitch). Currently we seek applications for

1 Postdoc: evolutionary immune genetics of mate choice (ref: 13/2009) The postdoc will co-ordinate the network, study the MHC of both study species and co-ordinate lab and field work in Berlin. The successful candidate will have a PhD in evolutionary genetics, zoology or related disciplines, a strong background in behavioural ecology, genetics and evolution, excellent knowledge of statistics, organisational skills, and a strong publication record. Experience in evolutionary immune genetics, particularly MHC, olfaction, and mammalian mating systems will be an advantage.

For an introduction to the publications of the participating groups see:

the role of MHC in mate choice - Sommer (2005) Frontiers in Zool; Ziegler et al (2005) Trends Immunol; Schwensow et al (2008) Proc R Soc Lond B; Schwensow et al (2008) Evol Ecol; spotted hyenas - East et al (2001) PNAS; East et al (2003) Proc Roy Soc Lond B; Höner et al (2007) Nature; Burgener et al (2009) Anim Behav; bats - Voigt & von Helversen (1998) Behav Ecol Sociobiol; Nagy et al. (2007) Proc R Soc Lond B; Voigt et al

(2008) J Mammal; Caspers et al. (2009) Behav Ecol Sociobiol.

All positions are limited to three years - starting dates are at the earliest on 1st September 2009. The IZW is determined to increase the proportion of women in successful scientific careers and particularly encourages female scientists to apply. For further information please contact Prof Dr Simone Sommer (immune genetics, +49-30-5168-315, sommer@izw-berlin.de), PD Dr Christian Voigt (bats, +49-30-5168-517, voigt@izw-berlin.de), Dr Marion East or Prof Dr Heribert Hofer (hyenas, +49-30-5168-512, east@ izw-berlin.de). Candidates should submit an electronic application with a letter clearly indicating which position they apply for, explain their interests in it and particular skills for it, enclose a CV, a summary of their PhD thesis (postdoc position), Diploma or Master Thesis (PhD positions), copies of relevant degrees, two letters of recommendation and publication list (if available) preferentially before 15 July 2009 (PhD positions) and 15 August 2009 (Postdoc position). We will consider applications until the position is filled and expect to hold an initial round of PhD candidate interviews on Friday 24 July 2009. Applications should be sent to the Leibniz-Institut für Zoo- und Wildtierforschung im Forschungsverbund Berlin e. V., Stephanie Vollberg, vollberg@izw-berlin.de, Postfach 60 11 03, D-10252 Berlin, Germany.

Prof Dr Simone Sommer

Evolutionary Genetics, Leibniz-Institute for Zoo- and Wildlife Research & Evolutionary Ecology, University of Potsdam Leibniz-Institute for Zoo- and Wildlife Research (IZW) Alfred-Kowalke Str. 17

D-10315 Berlin

Tel. +49 30 5168 315

Fax +49 30 5126 104

Postdoctoral position in comparative evolutionary genomics/human population genomics/statistical genomics at Penn State -

A postdoctoral position is available immediately in the laboratory of Kateryna Makova (http://www.bx.psu.edu/makova_lab/) at Penn State. The current focus of the lab is on deciphering molecular mechanisms of different mutations via whole-genome comparisons and on sex chromosome evolution.

As a successful candidate, you will come to our lab with relevant bioinformatics expertise, including some combination of programming experience, previous use of the R statistical package, and working knowledge of molecular evolution or population genetics. Once hired, you will analyze next-generation sequencing data sets and vertebrate genome alignments, and perform statistical and evolutionary modeling.

You will work in close collaboration with statisticians to develop computational models, with wet-lab biologists to validate model predictions, and with the GALAXY team (http://g2.bx.psu.edu) to implement our computational tools. You will be joining a dynamic group with an established record (http://www.bx.psu.edu/makova_lab/Publications.php). We are part of the Center for Comparative Genomics and Bioinformatics (http://www.bx.psu.edu/) and of the newly established Center for Medical Genomics at Penn State. Penn State is a vibrant scientific community with particular strengths in computational genomics and molecular evolution.

The starting date is flexible, with an earlier date preferred. Due to the nature of our projects, we would prefer a candidate who can commit for at least two years, but an extension of a contract for up to four years is possible.

Interested applicants should send pdfs with CV, a statement of research interests, and contact information of three references to kmakova@bx.psu.edu , indicating $B!H(Bpostdoctoral position$B!I(B in the subject line.

Kateryna Makova

Associate Professor

Center for Comparative Genomics and Bioinformatics, Department of Biology, 305 Wartik Lab, Penn State University, University Park, PA, 16802

Tel: 814-863-1619

Fax: 814-865-9131

E-mail: kmakova@bx.psu.edu

Web: http://www.bx.psu.edu/makova_lab/

A postdoctoral position is available at Harvard Medical School and Brigham and Women’s Hospital, Boston for Evolutionary Genomic studies in the laboratory of Dr. Charles Lee. Our lab focuses on understanding genomic structural variation particularly pertaining to evolution, population genetics of structural variation and disease associations (http://www.chromosome.bwh.harvard.edu). Ongoing research projects utilize array comparative genomic hybridization, DNA sequencing, RT-PCR and fluorescent in situ hybridization techniques, among others, to analyze structural genomic variation (Nature 444:444, 2006; Am J Hum Genet 82:685-695, 2008; Genome Res 18:1698, 2008). We are currently expanding a growing evolutionary group to complement ongoing projects in house and develop novel approaches for data analysis and production. Interested individuals must have or be close to obtaining a Ph.D. degree. In addition, applicants must demonstrate a high level of research productivity and writing proficiency through international, peer-reviewed publications.

The candidate should have a strong background in evolutionary biology and/or population genetics. Bioinformatic approaches relating to molecular biology and/or genetics as well as experience analyzing next generation sequencing or array-CGH data would be desirable. A background in computational and/or statistical methodologies as well as experience in statistical and/or programming languages (PERL, Python) would also be desirable.

Interested applicants should submit current curriculum vitae, statement of research experience and names of three individuals who can provide letters of reference electronically to: Dr. Omer Gokcumen

(ogokcumen@partners.org)

Two NIH funded postdoctoral positions will be available in September, 2009, in the laboratory of Montgomery Slatkin at the University of California, Berkeley.

One position is in the area of human evolutionary genetics, with particular emphasis on geographic variation in humans and on the relationship between humans and Neanderthals. Candidates should have training and research experience in theoretical population genetics, statistics and bioinformatics.

The second position is in the area of the population genetics of complex inherited diseases and resistance to infectious diseases.

Candidates should have training in human genetics, epidemiology, and statistics and should have some computer programming skills.

Both positions are for 2 years with the possibility of renewal for 2 additional years. The salary for the first 2 years will be $40,000 per year plus benefits. Applicants should send a letter, cv and names and email addresses of 3 references to Montgomery Slatkin <slatkin@berkeley.edu>. Review of applications will begin June 29, 2009. Information about the evolutionary genomics group in Berkeley is available at http://fisher.berkeley.edu/cteg/

POSTDOCTORAL RESEARCH ASSOCIATE 

MOUSE GENE MAPPING of BONE MORPHOLOGY and BIOMECHANICS in relation to OBESITY

Washington University School of Medicine

A position is available for a postdoctoral research associate to work on the genetics of bone morphology and biomechanics in relation to obesity and leptin levels.  We are currently fine-mapping QTLs affecting bone morphology and biomechanics to a sub-cM level in an advance intercross of LG/J and SM/J mice. Morphological measurements of long bones and vertebra will be collected from microCT scans and bones tested for their strength in response to controlled forces. Mapping analysis will identify small sets of positional candidate genes that will be evaluated using bioinformatics, and sequence and expression polymorphisms. Transgenic and complementation tests will be performed for select positional candidate genes.  We are especially interested in the context dependence of gene effects and the role of epistasis and genotype by environment interaction in the genetic architecture of complex traits.

It is desirable that candidates have some familiarity with bone biology and statistical analysis of gene mapping data.  The position is available immediately.  Interested candidates should submit a letter of application and their vitae to:

James M. Cheverud

Department of Anatomy & Neurobiology, Washington University School of Medicine, 660 S. Euclid Ave. St. Louis, MO, 63110, USA

E-Mail: Cheverud@pcg.wustl.edu

Phone: 314-362-4188

FAX: 314-362-3446

AA/EOE    M/F/D/V

POSTDOCTORAL RESEARCH ASSOCIATE

MOUSE GENE MAPPING and QTL IDENTIFICATION for OBESITY and DIABETES

Washington University School of Medicine

A position is available for a postdoctoral research associate to work on the genetics of obesity, diabetes, and diet-specific gene effects in mice.  We are currently fine-mapping QTLs affecting obesity, diabetes, and other metabolic syndrome traits to a sub-cM level in an advanced intercross of LG/J and SM/J mice. Positional candidate genes will be evaluated using bioinformatics, and sequence and expression polymorphisms. Transgenic and complementation tests will be performed for select positional candidate genes.  We are especially interested in the context dependence of gene effects and the role of epistasis and genotype by environment interaction in the genetic architecture of complex traits.

It is desirable that candidates have a familiarity with the molecular methods used in gene mapping studies, including development of genetic markers, primer design, sequence analysis, and gene expression studies using qPCR.  The position is available immediately.  Interested candidates should submit a letter of application and their vitae to:

James M. Cheverud

Department of Anatomy & Neurobiology, Washington University School of Medicine, 660 S. Euclid Ave. St. Louis, MO, 63110, USA

E-Mail: Cheverud@pcg.wustl.edu

Phone: 314-362-4188

FAX: 314-362-3446

AA/EOE    M/F/D/V

The Andrew W. Mellon Postdoctoral Fellows Program
Whittier College is a nationally recognized, selective, independent liberal arts college with a diverse student body of approximately 1300 undergraduates and is distinguished by its small size and innovative interdisciplinary programs.  The campus is located on a 95-acre hillside campus 18 miles southeast of downtown Los Angeles. We have a long history of commitment to equity, reflecting our Quaker origins, and our student body mirrors the diversity of the region.  We are an official Hispanic-Serving Institution and have had two Title V grants.  Our faculty, committed teacher-scholars, weave issues of diversity into their work with students.

Through the generosity of the Andrew W. Mellon Foundation, Whittier is pleased to inaugurate our Mellon Postdoctoral Fellows Program.  The program is designed to mentor new Ph.D.s through their first two years of teaching at a liberal arts college.   Fellows will teach one course during Fall terms and two during Spring terms, participate in interdisciplinary teaching, and help locate resources in their fields that provide global perspectives.   The program also allows time to plan one's scholarly agenda, grant-writing workshops, and some support for research expenses.

For academic year 2009-2010, we invite applications for two Mellon Postdoctoral Fellows in:
*       Sociocultural anthropology, with ethnographic experience and expertise in East Asia; preference for focus on China and Chinese diasporas
*       Musicology or  theatre specialist to teach courses on historical and/or comparative Asian music, theatre, dance, film

Review of materials (letter of application, vita/e, and a summary of the dissertation project) will begin immediately, and will continue until positions are filled.  Send application materials to: Susan Gotsch (sgotsch@whittier.edu), VPAA and Dean of Faculty, Whittier College (www.whittier.edu), 13406 E. Philadelphia St., PO Box 634, Whittier, CA, 90608.  We seek to attract and retain a highly qualified and diverse faculty (AA/EO).

[Inquiries about the Anthropology position may also be sent to Ann M. Kakaliouras, Assistant Prof. of Anthropology at akakalio@whittier.edu]
 

Post-doc in primate behavioral research

One post-doctoral position is potentially available in the Behavioral Biology Laboratory of the Institute for Mind and Biology at the University of Chicago (lab director: Dario Maestripieri; lab web site: http://primate.uchicago.edu).
The position involves research in behavioral neuroendocrinology with free-ranging rhesus monkeys on the island of Cayo Santiago, Puerto Rico. The position is for 18 months. To be considered for the position, email a copy of
your CV to dario@uchicago.edu. Review of applications will begin immediately. The position could be filled anytime in 2009 or 2010.

Qualifications/Experience:
Qualifications include a PhD in biology, psychology, or anthropology, experience with primate behavioral research in the field or in captivity, preferably with macaques or baboons, experience with collection and hormonal assay of fecal samples, knowledge of scientific literature in behavioral neuroendocrinology, and scientific publications in journals such as Animal Behaviour or Hormones and Behavior.

Salary/funding:NIH post-doctoral salary

Term of Appointment:the position could start anytime in 2009 or 2010

Application Deadline:no deadline

Contact Information:
Dario Maestripieri
5730 S. Woodlawn Avenue
Chicago, IL 60637
USA

Telephone Number:
(773) 834-4104

Fax Number:
(773) 702-0320

Website:
http://primate.uchicago.edu

E-mail Address:
dario@uchicago.edu

posted 10/30

Postdoctoral Fellowships: These three-year fellowship positions are open to U.S. citizens not currently in France wishing to work in the laboratories of the Institut Pasteur. Located in Paris and founded by Louis Pasteur in 1887, the Institut Pasteur is one of the world's leading private nonprofit centers for infectious disease research. With 2500 people of over 70 nationalities, its 130 research labs are devoted to the basic science of improving global public health. Application guidelines are available on the Pasteur Foundation website. The first step is to identify a host lab at the Institut Pasteur; please see website for details. Fellowship packages are $70,000 (stipends & bench fees) annually for three years. Upcoming Deadline: There will also be a call for applicants in February 2009.

ORISE Research Participation Program for the Joint POW/MIA Accounting Command, Central Identification Lab (JPAC-CIL) Deploying Anthropologist Fellowships

 The program provides opportunities to participate in ongoing osteological, bioarchaeological, and forensic anthropological research at JPAC/CIL.  Under the guidance of mentors, participants will have the opportunity to travel to locations of former U.S. military involvement, conduct archaeological excavations to recover human remains, and attempt to identify the remains in a laboratory environment.

Both post-doctoral and post-master's appointments are available.  Program participants must have previous experience supervising archaeological fieldwork and conducting osteological analysis.  They should have received the Ph.D., M.A., or M.S. degree in physical anthropology, forensic anthropology, bioarchaeology, zooarchaeology (with experience in human osteology), or a related field within five years of the desired starting date for post-doctoral candidates, or within three years of the desired starting date for post-master’s candidates.

The rigors of JPAC fieldwork require that participants be physically able to withstand harsh field environments for extended periods of time.  Otherwise, the program is open to all qualified U.S. citizens; without regard to race, sex, religion, color, age, physical or mental disability, national origin, or status as a Vietnam era or disabled veteran.

Participants will be selected based on relevant supervisory archaeological fieldwork, osteological lab experience, academic records, recommendations, applied research interests, compatibility of background and interests with the JPAC mission, and availability of funds.  Appointments are for one year and may be renewed for up to two additional years (post-master's) or four additional years (post-doctoral only) upon recommendation of JPAC and subject to availability of funds.  The appointments are full time at the host installation in Hawaii.

Stipends will be approximately $72,000 per year for a post-doctoral appointment and approximately $60,000 per year for a post-master's appointment.  Some inbound travel and moving expenses will be reimbursed according to established policies.  Travel and other costs may also be reimbursed for research or training related to the program if approved by JPAC.

Proof of medical insurance is required.  Health plans for participants are available through the Oak Ridge Institute for Science and Education.  This program for JPAC is administered by the Oak Ridge Institute for Science and Education (ORISE).  Applications are accepted and processed on a continuing basis.  For additional information or technical assistance with the online application process, contact:

 Lara Giordano

Oak Ridge Institute for Science and Education (ORISE)

4692 Millennium Dr., Suite 100, Belcamp MD  21017

Phone: (410) 306-9200 ext. 104    Email:  Lara.Giordano@orau.org

 For questions regarding program requirements, contact Dr. Joan Baker (Joan.Baker@jpac.pacom.mil or 808-448-1734).

 Information can also be found on the ORISE website http://www.orau.org/maryland/participants/apply.htm

and the JPAC website www.jpac.pacom.mil/index.php?page=employments_and_assignments&size=100&ind=0