The Lupus Foundation of America would like to alert you about a clinical trial that is taking place in your area. The MEDI 545 Phas II Study (MI-CP179) will evaluate the safety and tolerability of an investigational new drug for people with moderately to severly active lupus. Study participants must be at least 18 years old and have a positive ANA test. In addition, participants must not be pregnant or planning to become pregnant.